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Symbol
Name
ID
Il1r1
interleukin 1 receptor, type I
MGI:96545
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Human Phenotypes
Anemia
Elevated erythrocyte sedimentation rate
Disease(s) Associated with IL1R1
chronic recurrent multifocal osteomyelitis

Mouse Phenotypes
impaired neutrophil chemotaxis
decreased T cell proliferation
enlarged spleen
decreased eosinophil cell number
decreased neutrophil cell number
decreased T cell number
abnormal spleen morphology
abnormal neutrophil physiology
decreased immunoglobulin level
abnormal microglial cell activation
Availability Mouse Genotype
Il1r1em1(IMPC)Ccpcz/Il1r1em1(IMPC)Ccpcz
Il1r1tm1Imx/Il1r1tm1Imx
Il1r1tm1Quan/Il1r1tm1Quan
Il1r1tm1Roml/Il1r1tm1Roml
Il1r1tm1Quan/Il1r1tm1Quan
Tg(Tek-cre)12Flv/0  (conditional)
Il1r1tm1Quan/Il1r1tm1Quan
Lyz2tm1(cre)Ifo/Lyz2tm1(cre)Ifo  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory